It reminds me of a friend of mine... she's naturally butch. She's very happy the way she is, but will sometimes feel pressured to dress or act more feminine. Every time she does, though, she ends up looking like a dude in drag. XD
So a friend of mine on FB posted yours about the cat bugging you on the toilet, and I commented with the belief that it was a male character. Needless to say I was promptly corrected and then sent to this comic.
I like it. Your comic (not just this episode) has reminded me of how much female characters in comics tend to be overloaded with female signifiers, much more so than most of the people I know in real life. You have inspired me to try less hard to make my women look womanly and my men manly.
… Should I ever get around to drawing another episode, that is.